L-Theanine

L-Theanine is an amino acid that does not fall under the protein classification and is sourced from tea leaves, specifically green and white tea leaves. It is known to initiate alpha-wave production in the brain, which is essential to stay alert and aware while being calm and relaxed at the same time. It also assists in regulating bodily functions which would otherwise be altered by any kind of stress.


Nowadays it is not only humans who experience anxiety in this competitive world. Canine anxiety is among the commonest problems for pet owners. As a natural amino acid, L-theanine is known to relieve anxiety, sleep disorders, and aggression in pets. It has health benefits for cats, as well.




What the research says.
L-Theanine Alleviates Stress-Related Behaviors in Cats by Modulating Glutamatergic Pathways and Reducing Stress Scores
The use of L-theanine has been shown to reduce stress-related behaviors in cats. Research demonstrated that cats who were given 25 mg of L-theanine on a daily basis for a period of one month showed remarkable improvement in their respective stress scores or had their difficulties with stress reduced by 91% as shown by the results of the stress assessment tests. Some studies suggest that L-theanine has the ability to help relieve stress thanks to its ability to affect the behavior of the glutamate neurotransmitter system making this substance an attractive candidate for potential use in behavior management of cats.

L-Theanine Enhances Immune Function and Stress Resilience by Modulating Cytokine Balance, Neurotransmitters, and Cortisol
L-theanine contributes to enhancing the immune system by controlling the concentrations of immune cytokines, neurotransmitters, and the associated signalling pathways. Research has shown that it can decrease the level of pro-inflammatory cytokines, change the Th2/Th1 immune balance, raise levels of dopamine and serotonin, and decrease the level of the stress hormone named corticosterone. The studies suggest that L-theanine may strengthen the body's ability to fight diseases thanks to immunomodulatory and anti-stress mechanisms, thus providing a perspective in nutrition for improving the immune system health of pets as well as their emotional state.

L-Theanine Promotes Neurogenesis via Slc38a1 Regulation and Glutamine Transport in Neural Stem Cells
By regulating the expression of the Slc38a1 gene in neural stem cells, L-theanine can induce neurogenesis thereby may conderive neuroprotective effects. Research has shown that L-theanine is capable of increasing the differentiation of neural progenitor cells into new neurons, possibly through increasing the conversion of glutamine as well as enhancement of pathways involved in neurotransmitter metabolism, which in turn preserve brain function.

L-Theanine as a Natural Feed Additive in Poultry Nutrition: Antioxidant, Immunomodulatory, and Anti-Stress Benefits
L-theanine is a special type of amino acid that is a non-protein amino acid that is found in green tea. It provides many benefits in poultry nutrition, as it is responsible for biological activities including that of an antioxidant, immunity booster, and anti-inflammatory agent. Research has shown that L-theanine is able to help animals improve their health status thanks to its ability to reduce oxidative damages, increase the activity of antioxidant enzymes, enhance the functioning of the immune system, and decrease the level of stress hormones in the body.

L-Theanine Attenuates Stress in Aged Animals by Restoring Hippocampal Npas4 Expression and Modulating Neural Excitation-Inhibition Balance
L-theanine has been shown to reduce stress reactions in old animals via its inhibition of Npas4 expression in the hippocampal region of the brain. Studies indicate that L-theanine treatment can block the dysregulation of the genes that are linked to stress and that it contributes to the recovery of the Npas4 expression level, thereby lowering stress levels in the organism. Evidence shows that L-theanine has been shown to offer anti-stress effects through modulation of the balance between excitation and inhibition in the nervous system and related transcriptional processes, thus showing the importance of this compound for nutrition in terms of emotional control and support for the brain of aging animals.